Saint Andronicus Apostle of the Seventy and Saint Junia were relatives of the holy Apostle Paul. They labored much, preaching the Gospel to pagans. Saint Paul mentions them in his Epistle to the Romans: “Salute Andronicus and Junia, my kinsmen and fellow prisoners, who are of note among the Apostles, who also were in Christ, before me” (Romans 16:7).
Saint Andronicus was made Bishop of Pannonia, but his preaching also took him and Saint Junia to other lands, far from the boundaries of his diocese. Through the efforts of Saints Andronicus and Junia the Church of Christ was strengthened, pagans were converted to the knowledge of God, many pagan temples closed, and in their place Christian churches were built. The service in honor of these saints states that they suffered martyrdom for Christ.
In the fifth century, during the reign of the emperors Arcadius and Honorius, their holy relics were uncovered on the outskirts of Constantinople together with the relics of other martyrs at the gate of Eugenius (February 22).
It was revealed to the pious cleric Nicholas Kalligraphos that among the relics of these seventeen martyrs were the relics of the holy Apostle Andronicus. Afterwards, a magnificent church was built on this spot.